There are no discernible differences between the quality of cannabis oil in each pen. Every cartridge is made with top of the line cannabis extract. What matters most is preference. Each strain and oil type will lock in and provide their own special combination of cannabinoids and terpenes. If you like light floral flavors, go with a LIVE Pen. If you want a gassy taste, a CURED pen will do the trick. Try them all and see which terpenes work for you. Choose your entourage.